A. Carbone le 14/04/2015 au Colloquium d'informatique

Bonjour à tous,

C'est avec plaisir que nous vous convions à assister au prochain
exposé organisé dans le cadre du Colloquium d'informatique de l'UPMC
Sorbonne Universités : http://colloquium.lip6.fr/

The new era of biology is computational

présenté par Alessandra Carbone, professeure à l'Université Pierre et
Marie Curie

Ce colloquium s'adresse à un public large, et est ouvert à tous les
chercheurs et étudiants en informatique.

L'exposé aura lieu:
Mardi 14 avril 2015 à 18h
Amphithéâtre 15
Université Pierre et Marie Curie
4, place Jussieu (métro Jussieu)
75005 Paris

Pour s'y rendre :
http://www.upmc.fr/fr/universite/campus_et_sites/a_paris_et_en_idf/jussieu.html

Un cocktail est prévu à 17h15 en prélude à la conférence.

===== Abstract:

Biology entered a new era, with bioinformatics producing biological data
that are impossible nowadays to obtain with wet experiments. Soon
scientists and clinicians will use new DNA technologies to detect
mutations driving cancer and other diseases, identify new strains of
pathogens, map the physiological effects of the microbial communities
residing in our organs, track subtle changes in our immune repertoire,
predict drug response, and make innumerable other contributions to our
health and knowledge of complex biological systems. The scale and
complexity of the data will vastly exceed anything the biological and
medical community has faced before. Tackling these questions with
advanced engineering, new computer algorithms and novel computational
approaches is a challenge that will lead to revolutionize biology and
medicine through deeper, ubiquitous use of DNA information. Among
different examples, we shall present a computational approach to
protein-protein interactions that we developed within a project on
neuromuscular diseases. The project demands a high computational power
to test billions of interactions, it run on the machines of the World
Community Grid for more than 3 years, and provided a huge amount of
information on the interaction of human proteins. High Performance
Computing helped to obtain an unprecedented amount of information on
protein-protein interactions between real partners but also, and most
importantly, between non-partners.

===== Short bio:

Alessandra Carbone is Professor of Computer Science at UPMC and she has
led the Analytical Genomics team since 2003. She is the director of the
Laboratory of Computational and Quantitative Biology, created in January
2009 by CNRS and UPMC with the aim of developing an interdisciplinary
working environment made of several groups of theoreticians and
experimentalists interested in bioinformatics and modeling of complex
biological systems, systems biology, population genetics.
Alessandra Carbone received the Prix Joliot-Curie in 2010 from the
Ministère de la Recherche et de l’Enseignement Supérieur and from the
EADS Foundation, and she was distinguished in 2012 with the
Grammaticakis-Neuman Prize of the Académie des Sciences for “Integrative
Biology”. Since 2013 she is a senior member of the Institut
Universitaire de France.